Endocrine Abstracts

Glucagon-like peptide-1 (GLP-1) is an increatin hormon with various glucoregulatory effects, and exenatide is a GLP-1 receptor agonist used in the management of type 2 diabetes mellitus. C cell hypertrophy was seen in animals treated with GLP-1 receptor agonists, but the effects of GLP-1 agonists on C-cell proliferation or neoplasia in humans have not been documented formerly. The aim of this study was to evaluate the impact of exenatide on structural and functional features o...

Introduction: High level of Parathormone (PTH) impair bone health by increasing the risk of fracture. The aim is to determine the threshold value of PTH elevation to accompany deficiency or failure of Vit D. This may be an important parameter in assessing bone metabolism in clinical practice.Material and method: 931 patients who were referred to the endocrinology clinic were retrospectively studied and 880 patients diagnosed with Vit D deficiency include...

Aim: Hashimoto’s thyroiditis (HT) is the commonest autoimmune thyroid disease. Papillary thyroid cancer (PTC) is the most often thyroid cancer and its incidence is increasing yearly. It is not clear that HT is a predisposing factor for PTC. We studied PTC’s frequency among HT patients went to total thyroidectomy.Materials and methods: Five hundred and thirty four patients done total thyroidectomy by general surgery were evaluated retrospectivel...

Background: The inflammation of the pituitary gland known as hypophysitis. It is a rare disease accounting for approximately 0.24–0.88% of all pituitary diseases. Main forms of hypophysitis are histologically classified as lymphocytic, granulomatous, IgG4 related and xanthomatous. We aim to present ourpatients of hypophysitis with clinical,laboratoryand radiological features.Methods: We retrospectively reviewed our database of 1293 patients diagnose...

Aim: There are studies showing that Hashimoto’s thyroiditis (HT) progresses more rapidly, thyroid echogenicity is lower and thyroid autoantibodies are higher titer positive in immunoglobulin G4 (IGg4) positive patients.But a small number of studies that do not support this data have also been published.We planned this study to evaluate the findings of IgG4 (+) Hashimoto’s thyroiditis cases.Materials and methods: New diagnosis without treatment ...

Introduction: Hyperthyroidism is the condition that occurs due to excessive release of thyroid hormone by the thyroid gland. Anti-thyroid drugs are usually the first choice of the treatment but surgery and radioactive iodine can also be used in treatment of hyperthyroidism. Plasmapheresis is a rapid and effective treatment option in cases where immediate euthyroidism is needed to be obtained due to complications of thyrotoxicosis and major side effects of antithyroid drugs.</p...